Posted On: October 24th 2026, 02:18 pm
I get this question more than any other: “Do I have to come off my SSRI before psilocybin?” 🍄🟫
For years the answer was an automatic yes. But when you look at the actual research, it’s not so clear. One study says stopping might hurt your results, one says it doesn’t matter, and one says staying on is fine. Nobody has actually run the head to head trial yet.
So I broke down all four studies for you. Swipe through ➡️
Then tell me in the comments: if it were your call, would you stay on or come off? 👇🏼
Save this for later, and send it to someone who’s been asking about psychedelic assisted therapy.
Education only, not medical advice. Please don’t stop taking any medication before talking to your provider.
#psychedelictherapy #psilocybin #psilocybintherapy #SSRI #antidepressants