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It’s no secret that GLP-1 medications, like Ozempic, Wegovy, and Mounjaro, have helped millions of people across the globe — including professional athletes — with weight loss, appetite regulation, and blood sugar control. That said, there are many, many side effects that come with taking the increasingly popular drugs. For example, you’ve probably heard of the term “Ozempic face,” which refers to the sagging of the facial skin that can occur after extremely rapid weight loss. Per the Cleveland Clinic, some more GLP-1 side effects include nausea, hair loss, and “Ozempic butt” — aka muscle loss in the backside.

Well, this week on X, several social media users discovered a lesser-known side effect that some GLP-1 users have reported experiencing: “Ozempic vagina.” In response to a viral post about “the rise of Ozempic vagina,” one user tweeted, “a close friend verified that it happened to her and she let me see but more importantly, she let me gasp and laugh in shock because that MF really slid DOWN.” The post quickly racked up more than 3 million views and has prompted several people to question: What on earth is “Ozempic vagina?”

Well, according to Medical News Today, “Ozempic vagina” or “Ozempic vulva” refers to changes in the “appearance and comfort of the genital area” following rapid weight loss. Per the outlet, people who have experienced “vulvovaginal changes” report experiencing “loss of volume and plumpness in the labia majora and mons pubis,” “sagging or wrinkled skin,” and “changes in the shape of the vulva.”

(To be clear, there is no official scientific research that reports on “Ozempic vagina,” and while weight loss can certainly result in looser skin in the genital area, other factors — like fluctuating hormones — might also explain changes.)