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Stephanie Mandell

@stephaniemandell

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🎙️Podcast Producer | 🎬Talent Booker
🔗Connecting People to Audiences
🎤Going Public |Top Ranked Apple Podcast
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Everyone’s talking about peptides. Almost no one’s talking about the other half of the equation. 🧬 Here’s what surprised me even after years in medicine: about 1 in 3 of your body’s own peptide hormones come pre-attached to sugar chains called glycans — and that sugar is what keeps them from being shredded in minutes. Three you already know: 🩸 EPO — ~40% sugar. The blood hormone athletes get banned for. 🤰 hCG — ~30% sugar. The pregnancy hormone home tests detect. 🦋 TSH — your thyroid’s master switch, same sugar signature. Strip the sugar off any of them and the hormone falls apart — cleared in minutes, signal lost. Glycans aren’t just decoration on hormones, either. They form the glycocalyx — the fuzzy coat on every cell, including the lining of every blood vessel you have. When that vascular coat thins out (high blood sugar, inflammation, smoking), it’s one of the earliest signs of cardiovascular trouble. So here’s how I think about it: 👉 Peptides are the message. 👉 Glycans are the language — and the protection around it. 👉 Your gut, vessels, and immune system are the terrain it all runs on. The next frontier in longevity isn’t a single molecule. It’s supporting the whole communication system at once. Nature never optimized one and ignore the other — and neither should we. #glycans #peptides #medicine #health #drstefanomd
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You never know what someone is carrying. The person who snapped at you. The friend who went quiet. The stranger who was short with you. So often it has nothing to do with you — it’s the visible edge of a weight you cannot see. We spend so much energy judging behavior and almost none imagining the story underneath it. Here’s what I keep coming back to: Everyone is fighting something. And the most powerful thing we can offer each other isn’t judgment — it’s grace. Grace costs nothing. Kindness spreads faster than almost anything else we do. One softened moment can change someone’s entire day — and they carry it to the next person, and the next. You can’t fix what everyone is going through. But you can be the reason their day got lighter instead of heavier. Be kind before you know the reason. The world has never needed it more. ❤️ if this is your reminder today. Send it to someone who makes the world softer. 👇 #Kindness #grace #community #wellness #drstefanomd
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1 in 5 post-9/11 veterans has a traumatic brain injury. Veterans with a TBI diagnosis have a 94.3% higher crisis rate than those without. The standard of care has not meaningfully changed since 1980. That is the gap that is costing lives. The peer-reviewed evidence for what veterans with TBI and PTSD actually need already exists: 🧠 Transcranial photobiomodulation — laser therapy targeting neuroinflammation at the cellular level 🧠 NAD+ restoration — addressing mitochondrial dysfunction driving cognitive decline and mood dysregulation 🧠 DHA supplementation — three randomized trials showed benefit when given within 120 hours of brain injury 🧠 Hyperbaric oxygen therapy — growing peer-reviewed evidence for neurological recovery 🧠 Intrathecal regenerative therapy — neurotrophic factors placed directly where the damage occurred None of these are standard VA protocol. A May 2026 VA study confirmed that veterans with multiple toxic exposures — burn pits, heavy metals, chemical agents — have up to 17% higher odds of crisis-level psychological distress. They came home carrying something the standard of care was not built to treat. And they deserve better than a system that has not updated its TBI protocol since the Reagan administration. Drop a ❤️ for every veteran who came home different and was never told these options exist. Save this. Share it with a military family today. If you or a veteran you love needs support right now — call or text 988, press 1. Available 24/7. 📌 VA 2025 Annual Report. Brain Sci. 2025;15(3):234. Stars and Stripes, May 2026. #VeteranHealth #TBI #PTSD #medicine #drstefanomd
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People kept asking me why I am doing this. Why are you getting people together on a Wednesday? You are a spine surgeon. What does this have to do with your industry? And the answer is simple. We are living in a digital age where everyone is staring at their phones and missing the human connection that actually changes lives. The businesses that get started in these rooms. The friendships. The conversations that shift everything. I have been to these masterminds all over the country and I can tell you firsthand. The rooms you put yourself in determine the trajectory of your life. Whether you are here to get over a heartbreak, take your business to the next level, or just find your people. This is what it is about. Find your tribe. Protect your energy. And get in the rooms. #Entrepreneur #Mindset #Community #DrStefanoMD #WellnessAtTheSpeedOfLight
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The importance of being in the right rooms. The importance of finding our tribe. The importance of our shared humanity. Make the decision to get in rooms like we had this last Wednesday in Minneapolis because it may just change the way you see things, and even may change your entire life. #rooms #community #humanity #wellness #drstefanomd
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Ten cases today. Morbidly obese patients. Serious structural problems. Cases other surgeons turned down. And I need to say something that might make some of my colleagues uncomfortable. Stop saying no to patients who need you. I get it. Morbidly obese spinal surgery is hard. The risk profile is higher. The exposure is more complex. The anesthesia is more demanding. Every variable is more challenging. I am not dismissing that. But there is a difference between a surgeon who says “let’s optimize you medically before we operate” — which is the right call for elective cases where timing allows — and a surgeon who looks at a patient with progressive disability or even deficits, a closing window for intervention, and real permanent damage accumulating in real time — And says no because the case makes them uncomfortable. That second surgeon is failing their patient. And here is the part that actually keeps me up at night: When enough surgeons make that decision — the skill to safely do these cases disappears. You do not maintain surgical capability by avoiding difficult patients. You build it by showing up for them. Consistently. Over years. Through the cases that test your training and push your technique and make you better at the cases that come after. I finished case number ten an hour ago. I am already thinking about tomorrow. Because the patients sitting at their seventh surgical opinion did not run out of options. They just ran out of surgeons willing to show up. Tag a patient who deserved a yes and got a no. This needs to be said. 👇 #SpineSurgery #PatientFirst #SurgicalEthics #MorbidObesity #drstefanomd
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A Beverly Hills living room. One of the most powerful women in the world. And a conversation that is about to change how you think about every room you have ever walked into. @mariediamondofficial — Feng Shui grandmaster, featured teacher in The Secret, advisor to Grammy winners, Oscar recipients, and some of the most successful people alive — just sat down with me for Wellness at the Speed of Light and said something in the first five minutes that I have not stopped thinking about since. “The room you are sitting in right now is either giving you energy or stealing it. There is no neutral.” No neutral. Think about that for a second. The desk you work at. The bed you sleep in. The direction you face when you make your most important decisions. Marie has spent decades proving — with thousands of transformed lives as her evidence — that these are not aesthetic choices. They are energetic ones. And the difference between a space that supports your health, your creativity, and your vitality versus one that quietly depletes it is something most people spend their entire lives never understanding. Feng Shui is not what you think it is. It is not candles and crystals and moving your couch three inches to the left. It is the 3,000-year-old science of understanding that you are in constant energetic relationship with the space around you — and that relationship is either working for you or against you. I went to Beverly Hills to understand it firsthand. What I came back with changed how I look at every space I walk into. This is just the teaser. The full episode of Wellness at the Speed of Light is coming and I promise — you have never heard a conversation like this one. Follow. Turn on notifications. Tag someone whose environment you think might be holding them back. 👇 #MarieDiamond #FengShui #WellnessAtTheSpeedOfLight #TheSecret#drstefanomd
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Partying with the Rich & Famous🔥
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Do the math: 5 audacious moves a day = 25 a week = 1,300 a year. 🤯📈 In this clip from Business at the Speed of Light @scottdclary breaks down the exact math behind how fast your life can change if you just stop playing it safe. You don’t need 100 enterprise clients to change your business. You don’t need 50 investors to lead a funding round. You just need ONE. But to get that one, you have to take the big shots. If you send 5 “audacious” emails, DMs, or pitches every single day to the exact people you want to target, that compounds to 25 big swings a week. Even if 99% of them ignore you, the 1% that replies will change the trajectory of your entire life. Stop waiting for permission. Start taking the shots. Call to Action: Drop a 🎯 in the comments if you’re taking 5 big shots today. Listen to the full masterclass with Scott Clary when it drops next Monday! #ScottClary #SuccessMindset #BusinessGrowth #TakeTheShot
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👉👉👉Most people think luxury is about the house… It’s not. It’s the experience. The details. The way your day actually feels when you wake up. Coffee that becomes a ritual. Food that feels like art. Moments that slow you down… and others that remind you how alive you are. That’s what people are really chasing right now. Not just in Costa Rica… Not just in Florida… But a completely different way to live. Because the right home doesn’t just check boxes— It changes everything about your life. 👉 If you could design your ideal lifestyle from scratch… what would it look like? #LuxuryLifestyle #DesignYourLife #OceanLiving #CoastalLuxury #LiveDifferent
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The “Ortho vs. Neuro” spine debate is a trap. Yes in some conditions it may make sense but generally, this is asking the wrong questions! As a spine surgeon and President/CEO of a combined Ortho-Neuro practice, I’ve hired, managed and work daily with both. I see the raw data the public doesn’t. The medical literature is clear: analyzing tens of thousands of surgeries reveals ZERO statistical difference in outcomes between the two titles. If you pick a surgeon based on the letters on their door, you are gambling with your spine. Stop looking at their department and start auditing these 3 metrics: 1️⃣ Fellowship Training (highly specialized) Did they complete a dedicated spine fellowship? Those that put in the sweat and effort to go through these intense training programs are more equipped to handle complex spine surgery cases and this is really not something in question. 2️⃣ The Reps (Specific Case Volume) Don’t ask, “How many surgeries do you do?” Ask, “How many times have you done this exact procedure in the last 12 months?” High volume equals shorter OR times and fewer complications. Reps dictate mastery. 3️⃣ The Whisper Network (Actual Reputation) Online reviews are a baseline, but the real cheat code is asking the hospital staff. Ask the OR nurses, scrub techs, and local physical therapists who they would send their own mother to. Staff see what happens behind closed doors when things go wrong. Their unvarnished opinion is the ultimate metric. Making the difficult decision on who is going to take care of your spinal condition should be based on these three metrics rather than on whether a doctor is a neurosurgeon or an orthopedic spine surgeon. Let me know if you’ve had experience with one of these specialties or both treating you for your spine condition and what your experience was and your thoughts on this debate. I’ll answer each and every one of the questions myself. 📲 SAVE this post. Pull it out in the waiting room and use it as your checklist before signing a consent form. 🗣️ SHARE this with someone dealing with back pain before they make a permanent mistake. #spinesurgery #orthopedics #neurosurgeon #health #drstefanomd
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