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Dr. Ayesha Appa - Addiction & Infectious Diseases Doctor

@ayeshaappamd

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👩🏽‍⚕️ Your doctor friend for bugs, drugs, health
🏥 Head of Medical @bouldercare
🦠 UCSF-trained Addiction + ID
✌🏾 Mom | 👯‍♀️ Millennial | Views mine
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What happens when conventional herpes treatment fails? 🦠 Acyclovir, valacyclovir and famciclovir have long been the mainstay of HSV treatment. But in immunocompromised patients, refractory infections can be particularly challenging to manage. Enter PRITELIVIR ! A first-in-class oral helicase–primase inhibitor with a completely different antiviral target. With its recent FDA approval, pritelivir introduces a new treatment option for refractory mucocutaneous HSV infections in immunocompromised adults. And the Phase 3 results are worth discussing: 📊 63% vs 34% complete lesion healing by Day 28 compared with investigator-selected treatment. But what makes pritelivir different from acyclovir? Can it overcome antiviral resistance? And where does it fit into the current HSV treatment algorithm? I’ve broken down the mechanism, clinical evidence, dosing, safety and clinical positioning in this carousel. 👉 Swipe through to explore the pharmacology! 📩 Want the complete PDF? Comment ‘HSV’ below, and I’ll share it with you! Save • Share • Revise 📚 #pritelivir #antiviral #newdrug #medicine #pharmacology
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“But isn’t raw milk healthier?” I hear this a lot, and I get it. Pasteurized milk has essentially the same nutrition. What it doesn’t have is E. coli, Listeria, and Salmonella. The AAP just updated its policy this week, and the message is the same: pregnant women, babies, and kids get pasteurized only. Send this to the person who needs it. #rawmilk #foodsafety #pediatrician #momsofinstagram #wellness
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Did you hear?! It’s almost time… - - For IDWeek 2026 🦠 and I am so Excited!!! But I need your help! What are some Can’t Miss Lectures?! And how about content creation?! Currently seeing all the awesome content from Pediatricians at AAP so what are some ideas people want to see? Should I float around asking ID docs certain questions? Comment Below 😆🥹 even if ID is not your specialty #infectiousdisease #medstudent #pharmacy #womeninmedicine @idsainfo @shea_epi
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This is very common diagnosis in the hospital and soo many different approaches to it which can get confusing. So here’s my approach to bacteremia! A lot of updates here, so enjoy the learning! Comment “BACTEREMIA” if you want my approach!
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📌Healthcare sustainability: we don’t talk about it enough. We waste a lot in healthcare and all aspects of medicine, that leads to increase greenhouse gas emissions and pollution. 📌Check out this antibiotic waste calculator to learn more! 📌Don’t forget to follow @sidpharm @idsainfo @shea_epi 📌You can find the calculator right on the website or go through the resources page on the @sidpharm site #healthcare #waste #pollution #sustainabilty #medicine
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ID Doctor Responds to Appropriate/Inappropriate ID consults 🦠👩🏻‍⚕️💊 Long video compared to my usual but if you ever have to consult ID, I think it might help to watch! Thanks to @hospitaldoctort for the original video. If you’re not already following him, you should! Teamwork makes the dream work and the patient benefits from that! My take: 📌Don’t consult too early and don’t consult last minute 📌Absolute yes to ID consults for SAB, candidemia and complex scenarios that require prolonged therapy 📌Yes to starting the work up for the patient to get everything going ID Friends: what are some things you would add? @drrossanarosa @multilingualmd @ayeshaappamd @infectiousdrjulia #consult #infectiousdiseases #medicine #fyp
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So, 8/31 is International Overdose Awareness Day and many people don’t know this…so over the next few days I’m going to share a few posts on overdose recognition, prevention, and treatment. Let’s start with opioid overdose! We still see it far too often in our communities, EDs, hospitals, and ICUs. And with today’s increasingly unpredictable and contaminated drug supply, all of us should know how to recognize it and what to do next. So…let’s talk naloxone. We should be just as comfortable teaching naloxone as we are prescribing any other lifesaving medication. Overdose deaths have been moving in the right direction. Let’s keep pushing that number down. Save this one, share it with someone who should know how to use naloxone. What’s one thing about naloxone you think we still get wrong? #Naloxone #OpioidOverdose #OverdoseAwareness #AddictionMedicine #EmergencyMedicine
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You asked for it, and here it is! Managing alcohol use disorder doesn’t have to be complicated. These are some of the most common questions I get about treating AUD and ….I even added a Practice Shift flowchart for those of us who like to see it all laid out visually. Hopefully this makes things a little easier the next time you’re sitting with a patient with AUD and thinking, “Okay…where do I start?” Share this with a colleague, friend, or anyone who might find it helpful! What questions about AUD do you still have? Drop them below …I may make a Part 2.
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Here it is! Part 4 of things I used to do as a physician that I no longer do. These have honestly been some of the biggest practic shifts for me. And what surprised me most? A lot of physicians still haven’t made some of these changes yet. How many of these have you already changed in your own practice? And which one surprised you the most? Send this to a colleague Send this to patients
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You don’t have to wait until you’re in withdrawal to ask for help. If you’re using 7-OH regularly, being honest with a healthcare provider about how much you use, why you use it, and what happens when you stop can help you make a safer plan. And if 7-OH becomes harder to find, replacing it with pills bought online or from someone else can carry serious risk. Counterfeit pills may contain fentanyl, even when they look legitimate. Plan ahead. Ask questions. You deserve care that meets you where you are. #7OH #Kratom #HarmReduction #FentanylAwareness #AddictionTreatment
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The 7-OH ban could change access overnight. Dependence will not disappear with it. 7-hydroxymitragynine, commonly called 7-OH, occurs naturally in kratom in very small amounts. But concentrated 7-OH tablets, gummies, shots, and other products may contain much higher levels than traditional kratom leaf. The DEA has announced plans to place certain high-concentration and synthetic 7-OH products into Schedule I. This would not ban all traditional kratom products, but it could make covered 7-OH products illegal to manufacture, sell, or possess once the order takes effect. If you use 7-OH regularly and feel sick, anxious, restless, or unable to function normally when you stop, you may be experiencing withdrawal or dependence. You deserve support, not judgment. Start thinking about your plan before access changes. Avoid suddenly stopping alone, talk honestly with a healthcare provider about what and how much you use, and keep naloxone nearby whenever opioid-like substances may be involved. #7OH #Kratom #7OHBan #HarmReduction #Addiction #DEA
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If you use concentrated 7-OH regularly, now is the time to make a plan, not panic. Changes to 7-hydroxymitragynine access could leave some people dealing with withdrawal, cravings, worsening pain, anxiety, or pressure to find a replacement quickly. Suddenly stopping without support may be difficult, especially if you use 7-OH every day. A few harm reduction steps: • Talk with a healthcare provider before your supply runs out • Be honest about how much 7-OH you take and how often • Share what happens physically and emotionally when you stop • Explain whether you use it for pain, anxiety, opioid cravings, or withdrawal • Keep naloxone nearby and make sure someone you trust knows where it is • Avoid pills purchased online or from another person, since counterfeit pills may contain fentanyl • If you use other substances, try not to use alone Treatment for 7-OH dependence should be based on the individual. Some people may benefit from medications like buprenorphine for withdrawal or cravings. Others may need pain care, mental health support, peer support, or a combination. You do not have to wait until you are sick. You do not have to prove that your 7-OH use is “bad enough.” You deserve honest information, safer options, and care without judgment. #7OH #Kratom #HarmReduction #7OHban #Buprenorphine
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